MIDUS: Midlife in the U.S. National Study of Health and Well-Being


UW Institute on Aging and the National Institutes of Health


In 2022, the Midlife in the United States (MIDUS) National Study of Health and Well-Being started its second wave of longitudinal data collection of its refresher sample, new sample brought in to replenish the MIDUS longitudinal sample in 2011, contacting over 3,000 adults between the ages of 35 and 85 who had been MIDUS participants for nearly 10 years. The primary objective of the MIDUS study is to identify the major biomedical, psychological, and social factors that allow some people to achieve good health, psychological well-being, and social responsibility during the journey through middle life on into the later years. MIDUS Refresher 2 includes additional questions about the COVID-19 pandemic to investigate its effect on health and well-being. MIDUS Refresher 2 protocols include a 45-minute telephone interview, a 100-page mail questionnaire, and a 25-minute cognitive interview via telephone.

The MIDUS Refresher 2 includes a random oversample of 500 African American participants conducted in Milwaukee, Wisconsin, with protocols that include a 2-hour in-person interview, a 50-page questionnaire, and a 25-minute cognitive interview.


Karen Zoladz and Kerryann DiLoreto


MIDUS 2: January 2004 – September 2006
MIDUS 3: May 2013 – November 2014
MIDUS 3 Recontact: June 2017 – February 2018
Midus Retention Early Warning: September 2018 – March 2020

MIDUS Refresher 1: November 2011 – October 2014
MIDUS Refresher 2: November 2022 – Current